ParkinsonCanadaV1, Main, Exploration, bibRecord, 001173

Neurocognitive Speed and Inconsistency in Parkinson’s Disease With and Without Incipient Dementia: An 18-month Prospective Cohort Study

Identifieur interne : 001173 ( Main/Exploration ); précédent : 001172; suivant : 001174

Neurocognitive Speed and Inconsistency in Parkinson’s Disease With and Without Incipient Dementia: An 18-month Prospective Cohort Study

Auteurs : Cindy M. De Frias [États-Unis] ; Roger A. Dixon [Canada] ; Richard Camicioli [Canada]

Source :

Journal of the International Neuropsychological Society : JINS [ 1355-6177 ] ; 2012.

RBID : PMC:3804032

English descriptors

KwdEn :
- Aged, Aged, 80 and over, Cognition (physiology), Cohort Studies, Data Interpretation, Statistical, Dementia (complications), Dementia (psychology), Educational Status, Female, Humans, Longitudinal Studies, Male, Neuropsychological Tests, Parkinson Disease (complications), Parkinson Disease (psychology), Prospective Studies, Psychomotor Performance, Reaction Time (physiology).
MESH :
- complications : Dementia, Parkinson Disease.
- physiology : Cognition, Reaction Time.
- psychology : Dementia, Parkinson Disease.
- Aged, Aged, 80 and over, Cohort Studies, Data Interpretation, Statistical, Educational Status, Female, Humans, Longitudinal Studies, Male, Neuropsychological Tests, Prospective Studies, Psychomotor Performance.

Abstract

We examined two-wave longitudinal changes in two indicators of neurocognitive speed (i.e., mean rate, intraindividual variability) using one simple and three complex reaction time tasks. Participants included idiopathic Parkinson’s disease (PD) patients, with and without incipient dementia, and normal controls. At baseline, there were 45 patients (26 men, 19 women) with idiopathic PD who ranged from 65 to 84 years (M = 71.3, SD = 4.5) and 47 matched controls (27 men, 20 women) who ranged from 65 to 84 years (M = 71.4, SD = 4.9). The 18-month longitudinal sample comprised of 74 returning participants (43 controls, 31 PD patients) who had no cognitive impairment or dementia at both waves. Ten of the 31 PD patients returning for Time 3 had dementia or cognitive impairment. These constituted the PD with incipient dementia (PDID) group. Repeated measures analyses of variance showed that the PD and PDID groups were slower over time on the RT tasks whereas the controls improved their performance over time on all tasks. Inconsistency distinguished the two clinical groups (i.e., the PDID group but not the PD group became more inconsistent over time). Changes in neurocognitive speed and inconsistency may be valid clinical markers of PDID.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804032

DOI: 10.1017/S1355617712000422
PubMed: 22621940
PubMed Central: 3804032

Affiliations:

Canada, États-Unis
Texas

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La maladie de Parkinson au Canada (serveur d'exploration)

Neurocognitive Speed and Inconsistency in Parkinson’s Disease With and Without Incipient Dementia: An 18-month Prospective Cohort Study

Neurocognitive Speed and Inconsistency in Parkinson’s Disease With and Without Incipient Dementia: An 18-month Prospective Cohort Study

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson au Canada (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.